Searchable abstracts of presentations at key conferences in endocrinology

ea0015p261 | Pituitary | SFEBES2008

Effect of radiotherapy and pituitary dysfunction on mortality in patients with acromegaly

Sherlock Mark , Alonso Aurora Aragon , Reulen Raoul C , Ayuk John , Clayton Richard N , Sheppard Michael C , Hawkins Mike , Bates Andy , Stewart Paul M

Acromegaly is associated with increased morbidity and premature mortality which has been demonstrated in a number of retrospective studies reporting a standardised mortality ratio (SMR) between 1.3 and 3. Many patients with acromegaly develop hypopituitarism as a result of the pituitary adenoma itself or surgery and/or radiotherapy. Hypopituitarism is also associated with an increased SMR (1.2–2.17).Using the West Midlands Acromegaly database (n<...